(DOWNLOAD) "Use of Functionalized [Beta]-Lactams As Building Blocks in Heterocyclic Chemistry (Report)" by Pure and Applied Chemistry # eBook PDF Kindle ePub Free

eBook details

Title: Use of Functionalized [Beta]-Lactams As Building Blocks in Heterocyclic Chemistry (Report)
Author : Pure and Applied Chemistry
Release Date : January 01, 2010
Genre: Chemistry,Books,Science & Nature,
Pages : * pages
Size : 188 KB

Description

INTRODUCTION The class of [beta]-lactam antibiotics is generally recognized as a cornerstone of human health care due to the unparalleled clinical efficacy and safety of this type of antibacterials [1]. For example, the world antibiotics market is dominated by Augmentin, a combination of amoxicillin 1 and potassium clavulanate 2, produced by GlaxoSmithKline. Nevertheless, the recent appearance of highly resistant bacteria profoundly challenges the way medicinal chemists contemplate innovation of the [beta]-lactam structure and corroborates the need for continuous efforts within this field of research.